At a glance
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Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET
In Brief
A clinical study evaluating Cigarette Smoking, Computed Tomography, and 2 other interventions for Cigarette Smoking-Related Carcinoma. Completed, enrolled 21 participants across 1 site.
Detailed Summary
This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of nicotine in the respiratory tract and rate of uptake in the brain in current EC smokers. The results from this study may provide much needed scientific information to public health officials and regulators.
Study Details
Timeline
Interventions
Receive 1 puff of tobacco flavored protonated e-liquid
Receive 1 puff of unflavored protonated e-liquid
Receive 1 puff of tobacco flavored unprotonated cigarette
Receive 1 puff of unfavored unprotonated cigarette
Undergo PET/CT
Undergo PET/CT
Ancillary studies