CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 77 enrolled
Drug / intervention
Shambhavi Madamudra Kriyabehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05455814
NCT05455814N/ACompleted

Brain Health With Inner Engineering- Longitudinal Study of Shambhavi Mahamudra Kriya Meditation (BLISS)

Beth Israel Deaconess Medical Center·interventional·Posted Jul 13, 2022·Updated May 14, 2026

In Brief

A clinical study evaluating Shambhavi Madamudra Kriya for Meditation and Brain; Agenesis. Completed, enrolled 77 participants across 1 site.

Detailed Summary

This study will explore whether a 21-minute meditation practice called Shambhavi Mahamudra Kriya leads to changes in brain health and explore how it affects cognitive and physiological function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJul 13, 2022
Enrollment StartJan 6, 2023
Primary CompletionDec 16, 2025
Study CompletionDec 17, 2025
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 4.0 years ago

Interventions

Shambhavi Madamudra Kriyabehavioral

The intervention is taught at the Inner Engineering program offered by non-profit Isha Foundation as online as well as in-person formats. It incorporates a combination of different breathing patterns and meditative components. The intervention training provides precise, step by step and easy to follow instructions on how to perform this practice. Performed in a seated posture, this is a simple, safe and accessible intervention that requires no previous experience of meditation. The intervention selected for this study was shown to significantly reduce perceived stress, enhance self-reported general well-being, improve positive emotions, mindfulness, sleep, engagement, relationships, and may promote enhanced Heart Rate Variability and Sympathovagal balance.