At a glance
ClinicalIndex Comparison RecordN/ACompleted· 13 enrolled
Drug / intervention
splenic artery ligationprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Hemodynamic Modulations to Ameliorate Sinusoidal Injuries After Extended Liver Resections: the Role of Splenic Artery Ligation and Porto-caval Shunt in a Series of Patients
In Brief
An observational study evaluating splenic artery ligation for Small-For-Size Liver Syndrome and 7 related conditions. Completed, enrolled 13 participants across 1 site.
Detailed Summary
Our study aimed at assessing the changes of portal vein pressure, portal vein flow and hepatic arterial flow (HAF) in liver remnants ≤ 30% of the standard liver volume by reducing portal vein overflow via ligation of the splenic artery.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsSmall-For-Size Liver Syndrome, Ligation, Liver Regeneration, Splenic Artery, Portal Vein, Ischemia, Reperfusion Injury, Hepatectomy
CountriesGreece
Collaborators--
Timeline
N/ACompletedFinished
2017201820192020202120222023202420252026
Enrollment StartJan 2017
Primary CompletionDec 2021
First PostedJul 2022
TodayJul 2026
First PostedJul 15, 2022
Enrollment StartJan 1, 2017
Primary CompletionDec 31, 2021
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 4.0 years ago
Interventions
splenic artery ligationprocedure
We identified portal hyperperfusion as a cause of potential small-for-size liver remnant dysfunction and we applied splenic artery ligation as a technically simple procedure to manage the situation