CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Exercise +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05473000
NCT05473000N/ACompleted

Investigating Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise Based on Resting Ozone Exposure

University of British Columbia·interventional·Posted Jul 25, 2022·Updated Apr 13, 2025

In Brief

A clinical study evaluating Exercise, Ozone, and 1 other intervention for Ozone Exposure During Rest and Exercise. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function. The proposed study aims to have participants perform submaximal and maximal cycling exercise protocols exposed to both O3 and room air in a crossover design to evaluate how ventilatory patterns, pulmonary function, development of symptoms, and cycling performance are impacted by O3 exposure. Additionally, the investigators look to compare responses between O3 at rest and during exercise to predict which subjects may be most susceptible to adverse response, as considerable interindividual variability exists.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada

Timeline

N/ACompletedFinished
2023202420252026
First PostedJul 25, 2022
Enrollment StartAug 18, 2022
Primary CompletionJun 1, 2023
Study CompletionJun 1, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 3.9 years ago

Interventions

Exercisebehavioral

Submaximal and maximal exercise

Ozoneother

Delivery of ozone air pollution at 170ppb

Room airother

Delivery of room air