CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Experimental: Locomotor Learningbehavioral
Likely dose
Locomotor and turn learning through four sessions of practice walking over different terrains and obstacles at varying speedsAI-extracted
Key inclusion· 4
  • Age 65 years or older
  • Self-reported difficulty with walking tasks (e.g., fatigue walking a quarter mile, climbing two flights of stairs, household chores)
  • Preferred 10m walking speed less than 1.1 m/s
  • Willingness to be randomized and participate in all study assessments and interventions
Key exclusion· 14
  • Diagnosed neurological disorder or central nervous system injury (Alzheimer's, Parkinson's, stroke, etc.)
  • Contraindications to non-invasive brain stimulation (metal in head, scalp wounds)
  • Contraindications to MRI (metal in body, claustrophobia)
  • Use of medications affecting the central nervous system

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05475236
NCT05475236N/ACompleted

Brain Networks of Turning Performance With Aging and Stroke

VA Office of Research and Development·interventional·Posted Jul 26, 2022·Updated Jun 11, 2025

In Brief

A clinical study evaluating Experimental: Locomotor Learning for Aging. Completed, enrolled 16 participants across 1 site.

Detailed Summary

Older adults and stroke survivors often have difficulty performing complex walking tasks, due in part to changes in the brain. One task often overlooked is turning, which can lead to injury when performed poorly. The investigators will use non-invasive brain stimulation to assess brain activity and relate those observations to turning performance in older adults and stroke survivors.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAging
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJul 26, 2022
Enrollment StartFeb 28, 2023
Primary CompletionJun 28, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.9 years ago

Interventions

Experimental: Locomotor Learningbehavioral

Participants will undergo four sessions of locomotor and turn learning. Locomotor learning will involve practicing walking over different terrains (i.e., soft and firm mats) and obstacles at different walking speeds (slow or fast) and turning practice at each end of the walking course. The full cohort will undergo either transcranial direct current stimulation or sham stimulation.