CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 26 enrolled
Drug / intervention
Autologous facial fat graft injectionother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05482425
NCT05482425N/ACompleted

A Single Center, Randomized Study to Evaluate Skin Characteristics After Facial Autologous Fat Grafting to Both Sides of the Face Using Saline Washed or Unwashed Fat Graft.

University of Pittsburgh·interventional·Posted Aug 1, 2022·Updated Nov 5, 2025

In Brief

A clinical study evaluating Autologous facial fat graft injection for Facial Skin Texture and Facial Skin Pigmentation. Completed, enrolled 26 participants across 1 site.

Detailed Summary

The goal of this study is to specifically examine changes in facial skin appearance after facial fat grafting with autologous fat tissue that has either been washed with sterile saline before injecting, or left unwashed. This will be testing two variations of a standard of care surgical procedure, in two cohorts of subjects. One group will receive washed fat, and one group will receive unwashed fat, to both sides of the face. There are no experimental devices, drugs, or biological agents being used in this study. All fat tissue is autologous from the subjects treated. Significance: This study will provide evidence that may directly impact clinical practice for a common procedure in plastic surgery. Regardless of whether the null hypotheses is accepted or rejected, the data will be of direct clinical use and impact practice in the operating room.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedAug 1, 2022
Enrollment StartOct 17, 2022
Primary CompletionSep 30, 2025
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 3.9 years ago

Interventions

Autologous facial fat graft injectionother

Participants will received either a washed or unwashed autologous facial fat graft injection to both sides of the face, as determined by randomization.