CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 30 enrolled
Drug / intervention
demineralized and mineralized combination putty bone allograft +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05484492
NCT05484492Phase 4Completed
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Ridge Preservation Comparing the Clinical and Histologic Healing of Two Different Putty Bone Grafts

University of Louisville·interventional·Posted Aug 2, 2022·Updated Feb 10, 2026

In Brief

A Phase 4 clinical trial evaluating demineralized and mineralized combination putty bone allograft and calcium phosphosilicate putty alloplast graft for Alveolar Bone Resorption. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs. synthetic calcium phosphosilicate (CPS) putty alloplast graft utilization in socket preservation procedures. A regenerative tissue matrix membrane will be used to cover each graft lying below the flap.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlveolar Bone Resorption
CountriesUnited States
CollaboratorsBioHorizons, Inc.

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedAug 2, 2022
Enrollment StartOct 6, 2022
Primary CompletionOct 7, 2025
Study CompletionOct 30, 2025
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 3.9 years ago

Interventions

demineralized and mineralized combination putty bone allograftbiological

Subjects in this group will receive an intrasocket demineralized and mineralized combination putty bone allograft following tooth extraction

calcium phosphosilicate putty alloplast graftbiological

Subjects in this group will receive an intrasocket synthetic resorbable calcium phosphosilicate putty alloplast graft following tooth extraction