At a glance
ClinicalIndex Comparison RecordN/ACompleted· 15 enrolled
Drug / intervention
Hydroxyapatite toothpaste +1 moreother
Likely dose
10% Hydroxyapatite toothpaste versus 1450 ppm Sodium Fluoride toothpasteAI-extracted
Key inclusion· 6
- ✓Age 18-60 years
- ✓Good general health
- ✓Minimum 20 natural uncrowned teeth excluding third molars
- ✓Normal salivary flow rate (stimulated ≥0.7 ml/min, unstimulated ≥0.2 ml/min)
Key exclusion· 10
- ✕Advanced periodontal disease
- ✕Medical condition requiring pre-medication prior to dental visits/procedures
- ✕Impaired salivary function
- ✕Orthodontic retainers present
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste - an in Situ Study
The University of Texas Health Science Center at San Antonio·interventional·Posted Aug 3, 2022·Updated Apr 12, 2024
In Brief
A clinical study evaluating Hydroxyapatite toothpaste and Sodium Fluoride Toothpaste for Molar Incisor Hypomineralization. Completed, enrolled 15 participants across 1 site.
Detailed Summary
This study tests the remineralization of donor teeth (donorMIH) in situ in participants using 10% hydroxyapatite (HAP) toothpaste and sodium fluoride toothpaste.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMolar Incisor Hypomineralization
CountriesUnited States
CollaboratorsDr. Kurt Wolff GmbH & Co. KG
Timeline
N/ACompletedFinished
2023202420252026
First PostedAug 2022
Enrollment StartSep 2022
Primary CompletionDec 2022
TodayJul 2026
First PostedAug 3, 2022
Enrollment StartSep 6, 2022
Primary CompletionDec 9, 2022
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 3.9 years ago
Interventions
Hydroxyapatite toothpasteother
10% Hydroxyapatite toothpaste
Sodium Fluoride Toothpasteother
1450 parts per million sodium fluoride toothpaste