CI

At a glance

ClinicalIndex Comparison Record
Phase 3Recruiting· 30 target
Drug / intervention
Yutiq 0.18 MG Drug Implant +1 moredrug
Likely dose
Yutiq 0.18 MG Drug Implantfrom record
Key inclusion· 7
  • Male or non-pregnant female at least 18 years of age
  • Chronic noninfectious posterior segment inflammation with or without anterior uveitis
  • Prior clinical response to ≥1 corticosteroid treatment with recurrence indicating chronicity
  • Active posterior segment inflammation
Key exclusion· 13
  • Anterior uveitis only without posterior segment involvement
  • Vitreous hemorrhage present
  • Infectious etiology uveitis
  • Intraocular inflammation from condition other than noninfectious uveitis

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05486468
NCT05486468Phase 3RecruitingOn TrackUpdated 10mo ago
Long Recruiting

The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment (TYNI Trial)

Texas Retina Associates·interventional·Posted Aug 3, 2022·Updated Aug 11, 2025

In Brief

A Phase 3 clinical trial evaluating Yutiq 0.18 MG Drug Implant and Sham Injection for Uveitis and 3 related conditions. Currently recruiting, targeting 30 participants across 1 site.

Detailed Summary

The Use of Two YUTIQ versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment (TYNI Trial)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 3Recruiting
20232024202520262027
First PostedAug 3, 2022
Enrollment StartOct 5, 2022
Primary CompletionJul 1, 2026
Study CompletionDec 1, 2026
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 3.9 years ago

Interventions

Yutiq 0.18 MG Drug Implantdrug

YUTIQ ® (fluocinolone acetonide intravitreal implant) 0.18 mg, for intravitreal injection

Sham Injectionother

Sham injection