At a glance
ClinicalIndex Comparison Record- ✓Pregnant women age 18 or older
- ✓ASA Physical Status 2 or 3
- ✓Term pregnancy (≥37 gestational weeks)
- ✓Planning epidural labor analgesia
- ✕Pre-eclampsia (with or without severe features)
- ✕New antihypertensive medication started within 24 hours before enrollment
- ✕Uncontrolled systemic comorbidities (diabetes, hepatic, renal, or cardiac disease)
- ✕Known or suspected fetal abnormalities
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia: A Randomized Controlled Quadruple Blinded Non-Inferiority Trial (CLASSIER Trial)
In Brief
A Phase 2 clinical trial evaluating Clonidine, Dexmedetomidine, and 2 other interventions for Pregnancy Related. Completed, enrolled 88 participants across 1 site.
Detailed Summary
The purpose of this randomized controlled trial is to compare the effectiveness of epidural clonidine, dexmedetomidine, or fentanyl adjuncts for labor analgesia.
Study Details
Timeline
Interventions
Clonidine belongs to the drug classification of antihypertensives
Dexmedetomidine belongs to the drug classification of sedatives
Fentanyl belongs to the drug classification of analgesic opioid agonists and is used as the standard of care
Ropivacaine belongs to the drug classification of local or regional anesthesia for surgery and is used as standard of care