CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 471 enrolled
Drug / intervention
CT-P47 +1 morebiological
Likely dose
CT-P47 8 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05489224
NCT05489224Phase 3Completed

A Randomized, Active-Controlled, Double-Blind, Phase 3 Study to Compare Efficacy and Safety of Two Intravenous Infusion Formulations of Tocilizumab (CT-P47 and RoActemra) When Co-administered With Methotrexate in Patients With Rheumatoid Arthritis

Celltrion·interventional·Posted Aug 5, 2022·Updated Oct 8, 2024

In Brief

A Phase 3 clinical trial evaluating CT-P47 and EU-approved RoActemra for Rheumatoid Arthritis. Completed, enrolled 471 participants across 1 site.

Detailed Summary

This is a phase 3 study to compare efficacy and safety of CT-P47 and RoActemra in patients with moderate to severe active rheumatoid arthritis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPoland
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedAug 5, 2022
Enrollment StartSep 14, 2022
Primary CompletionJun 29, 2023
Study CompletionNov 23, 2023
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 3.9 years ago

Interventions

CT-P47biological

CT-P47, 8 mg/kg (not exceeding 800 mg/dose) by intravenous (IV) infusion every 4 weeks (Q4W)

EU-approved RoActemrabiological

EU-approved RoActemra, 8 mg/kg (not exceeding 800 mg/dose) by IV infusion Q4W