At a glance
ClinicalIndex Comparison Record- ✓Women older than 18 years
- ✓English-speaking
- ✓Stage greater than 2 pelvic organ prolapse
- ✓Undergoing pelvic organ prolapse surgery (vaginal, laparoscopic, mesh-augmented, or obliterative procedure)
- ✕Renal dysfunction with creatinine clearance less than 60 mL/min
- ✕Allergy to acetaminophen or ibuprofen
- ✕Allergy to gabapentin
- ✕Currently on a Controlled Substance Agreement or Opioid Contract from another provider
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Perioperative Gabapentin on Postoperative Opioid Requirements
In Brief
A Phase 4 clinical trial evaluating Preoperative Gabapentin/Postoperative Placebo and Preoperative Gabapentin/Postoperative Gabapentin for Postoperative Pain. Completed, enrolled 114 participants across 1 site.
Detailed Summary
The purpose of this study is to determine if preoperative gabapentin is noninferior to preoperative and postoperative gabapentin for pain control in patients undergoing surgery for pelvic organ prolapse.
Study Details
Timeline
Interventions
Postoperatively, this group will receive scheduled acetaminophen and ibuprofen every 6 hours, in addition to placebo every 12 hours. The placebo is encapsulated to appear identical to the active drug. This group will have oxycodone 5 mg every 6 hours as needed for pain.
Postoperatively, this group will receive scheduled acetaminophen and ibuprofen every 6 hours, in addition to gabapentin every 12 hours. The gabapentin is encapsulated to appear identical to the placebo. This group will have oxycodone 5 mg every 6 hours as needed for pain.