CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 30 enrolled
Drug / intervention
Lidocaine IV +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05501600
NCT05501600Phase 1Completed
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Neural Correlates of Lidocaine Analgesia

Keith M Vogt·interventional·Posted Aug 15, 2022·Updated Dec 24, 2024

In Brief

A Phase 1 clinical trial evaluating Peripheral Nerve Stimulation and Lidocaine IV for Anesthesia and Pain. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The purpose of this study is to characterize the effects of intravenous lidocaine on pain processing and cognitive function. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena. The study will consist of 1 visit and involves no long-term follow up.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnesthesia, Pain
CountriesUnited States
CollaboratorsNational Institute of General Medical Sciences (NIGMS)

Timeline

Phase 1CompletedFinished
2023202420252026
First PostedAug 15, 2022
Enrollment StartNov 22, 2022
Primary CompletionNov 17, 2023
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 3.9 years ago

Interventions

Peripheral Nerve Stimulationdevice

Experimental acute pain stimulus will be delivered using an electric nerve stimulator.

Lidocaine IVdrug

Subjects will receive an intravenous infusion of lidocaine for about 30 minutes.