CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 47 enrolled
Drug / intervention
Tooth extraction and ridge preservation using different barrier mermbranesprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05505084
NCT05505084N/ACompleted

Comparison of Five Distinct Membranes for Preservation of the Alveolar Ridge Following Tooth Extraction: A Prospective, Randomized, Controlled Clinical Study

University of Pennsylvania·observational·Posted Aug 17, 2022·Updated May 8, 2026

In Brief

An observational study evaluating Tooth extraction and ridge preservation using different barrier mermbranes for Tooth Fractures and 2 related conditions. Completed, enrolled 47 participants across 1 site.

Detailed Summary

Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies. Especially during the first three months followed by the tooth extraction, the volume of bone may change significantly without any interference. Thus, doing a ridge preservation procedure following the extraction is a common standard of care method to maintain the socket volume if implant placement is considered as a treatment option in the future. A variety of materials and methods have been used for ridge preservation. However, it's still inconclusive to determine the best material to maintain the ridge dimension, especially for membrane placement that allows for space maintenance to protect the grafting material. Furthermore, there is no evidence to show any treatment rationale is superior to any other ridge preservation method. In general, the membrane serves the function of the barrier and space protector. The periodontal surgeon use membranes to exclude the epithelium growth and to limit the collapse of the soft tissue into the healing alveolar socket. Regarding resorbable and non-resorbable membrane materials, both serve the function of protecting the graft material from the oral cavity. However, there are also many demonstrating that without membranes the extraction socket healed nicely without any interferences. The question to us is: Do we need the membrane to exclude the epithelium or any kind of surgical dressing material is sufficient enough to preserve the volume of the extracted ridge? The object of this study is to compare five popular membranes on the market that present different characteristics of the membranes.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsZimVie

Timeline

N/ACompletedFinished
2023202420252026
First PostedAug 17, 2022
Enrollment StartAug 15, 2022
Primary CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 3.9 years ago

Interventions

Tooth extraction and ridge preservation using different barrier mermbranesprocedure

The hopeless and unrestorable teeth are planned for extraction and implant placement.