CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 20 enrolled
Drug / intervention
Daratumumab and Hyaluronidase-fihj +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05511428
NCT05511428Phase 4Completed

Open Label Single Arm Study to Assess the Implementation of Home Based Daratumumab Administration in Patients Being Treated for Multiple Myeloma

Thomas Jefferson University·interventional·Posted Aug 23, 2022·Updated Nov 21, 2025

In Brief

A Phase 4 clinical trial evaluating Daratumumab and Hyaluronidase-fihj, Questionnaire Administration, and 2 other interventions for Plasma Cell Myeloma. Completed, enrolled 20 participants across 1 site.

Detailed Summary

This clinical trial tests the treatment effect of home based daratumumab administration in treating patients with multiple myeloma. Darzalex Faspro is a combination of two drugs (daratumumab and hyaluronidase) used to treat adults with multiple myeloma. Daratumumab is in a class of medications called monoclonal antibodies. It works by helping the body to slow or stop the growth of cancer cells. Hyaluronidase-fihj is an endoglycosidase. It helps to keep daratumumab in the body longer so that the medication will have a greater effect. Standard medical care requires Darzalex-Faspro treatment be administered during visits to the cancer center. Receiving medication in the home setting, may decrease cost and burden of care in patients with multiple myeloma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedAug 23, 2022
Enrollment StartNov 8, 2022
Primary CompletionMay 22, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 3.9 years ago

Interventions

Daratumumab and Hyaluronidase-fihjdrug

Given SC

Questionnaire Administrationother

Ancillary studies

Quality-of-Life Assessmentother

Ancillary studies

Interviewother

Ancillary studies