At a glance
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Improving HIV Prevention Among Adolescent Girls and Young Women (AGYW) in Uganda
In Brief
A clinical study evaluating Peer Support for HIV-1-infection. Completed, enrolled 394 participants across 1 site.
Detailed Summary
Purpose: The purpose of the project is to evaluate a peer support intervention aimed at improving uptake of and adherence to oral PrEP. Main Study Aim: To evaluate a peer support intervention aimed at improving uptake of and adherence to oral pre-exposure prophylaxis (PrEP), and its effect on sexual behavioral and reproductive health outcomes Study Objectives: i. To evaluate the effect of a peer support intervention on uptake of and adherence to oral PrEP among 14-24-year-old AGYW at risk of HIV infection in Kampala, Uganda. ii. To evaluate the effect of the peer support intervention aimed at improving oral PrEP uptake and adherence, on sexual behavior and reproductive health outcomes among AGYW in Kampala, Uganda. Design An individually randomized controlled trial with parallel group design and 1:1 randomization in the intervention and control arms. Population: 14-24-year old AGYW at risk of HIV infection in Kampala. Control arm: Standard health worker counselling during clinic visits. Intervention arm: Standard health worker counselling during clinic visits + peer support groups over the weekend.
Study Details
Timeline
Interventions
Peer-led support groups over the weekend will include the following activities: * Peer leader counselling on oral PrEP and HIV risk reduction * Peer leader discussion to dispel myths and misconceptions around oral PrEP * Peer leader sharing of experiences of daily pill taking * Participants sharing experiences of influencers and barriers to oral PrEP uptake and adherence followed by a discussion by group members. * 1-2 role plays per support group session.