CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 173 enrolled
Drug / intervention
multifaceted pharmacist-led intervention +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05521971
NCT05521971N/ACompleted

The Impact of a Pharmacist Intervention on Post-discharge Hypnotic Drug Discontinuation in Geriatric Inpatients: a Before-after Study

Universitaire Ziekenhuizen KU Leuven·interventional·Posted Aug 30, 2022·Updated Aug 30, 2022

In Brief

A clinical study evaluating multifaceted pharmacist-led intervention and Usual care group for Hypnotic Withdrawal. Completed, enrolled 173 participants.

Detailed Summary

This study investigated whether a multifaceted approach was associated with hypnotic drug discontinuation at one month after discharge

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedAug 30, 2022
Enrollment StartOct 11, 2016
Primary CompletionSep 19, 2019
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 3.8 years ago

Interventions

multifaceted pharmacist-led interventionother

* Educational sessions were provided to the physicians and nursing staff. * Discontinuation regimens were developed. Prescribers were free to choose whether or not to actually use them. The regimens were derived from the regimen used by Petrovic et al. and encouraged a switch from any benzodiazepine to lorazepam 1 mg OD for one week followed by drug stop. Z-drugs were switched to zolpidem 5 mg OD for one week followed by drug stop. If deemed necessary, a pro re nata regimen of lorazepam 1 mg or zolpidem 5 mg for one additional week was prescribed respectively. The discontinuation regimens were incorporated into the hospital's electronic prescribing system. Furthermore, a clinical decision support system provided additional support. * Patient education sessions were provided upon enrolment and at discharge. Specific patient leaflets were used to facilitate patient education. * The patient's primary care physician and, if applicable, the nursing home were informed by phone.

Usual care groupother

all patients received comprehensive geriatric care without any systematic clinical pharmacist involvement regarding deprescribing of hypnotics. Treating physicians were not actively informed on the patient's participation in this particular study.