CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 112 enrolled
Drug / intervention
Narcotrend Monitor (MT MonitorTechnik, Hannover, Germany)device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05525104
NCT05525104N/ACompleted

The Influence of Electroencephalographic Density Spectral Array Guidance of Sevoflurane Administration on Recovery From General Anaesthesia in Children Between 6 Months and 12 Years.

Erasmus Medical Center·interventional·Posted Sep 1, 2022·Updated Mar 11, 2025

In Brief

A clinical study evaluating Narcotrend Monitor (MT MonitorTechnik, Hannover, Germany) for Anesthesia and Depth of Hypnosis Monitoring. Completed, enrolled 112 participants across 1 site.

Detailed Summary

In this randomised, blinded study, we will investigate the influence of DSA on recovery from general anaesthesia. DSA monitoring provides continuous information on depth of hypnosis. Based on DSA monitoring dose adjustments of sevoflurane can be made. We expect that this will lead to a faster speed of emergence and recovery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesNetherlands
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedSep 1, 2022
Enrollment StartSep 5, 2022
Primary CompletionFeb 29, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 3.8 years ago

Interventions

Narcotrend Monitor (MT MonitorTechnik, Hannover, Germany)device

This trial is designed to investigate the additional value of Density Spectral Array monitoring, on the "speed of emergence" after general anaesthesia. We will compare traditional general anaesthesia with sevoflurane using a MAC value and subjective clinical parameters to the objective and continuous approach using DSA depth of hypnosis. The investigational product is the validated Narcotrend monitor, an electroencephalographic monitor, that is regularly used in anaesthesia practice in the Sophia children's hospital and will be used according to intended purpose. The extended version as used in the operating room in the Sophia Children's hospital offers a diversity of diagrams including Density Spectral Array. The electroencephalographic Narcotrend monitor records frontal EEG-activity. Standard paediatric ECG electrodes are used for EEG registration