At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase 1, Open-Label, Randomized, Single Dose, Crossover Study to Estimate the Relative Bioavailability of Nirmatrelvir and Ritonavir Following Oral Administration of 4 Different Fixed Dose Combination Tablet Formulations Relative to The Commercial Tablet Formulation in Healthy Adult Participants Under Fasted Conditions
In Brief
A Phase 1 clinical trial evaluating Nirmatrelvir/ ritonavir and Nirmatrelvir/ritonavir for Biological Availability and Healthy Participants. Completed, enrolled 15 participants across 1 site.
Detailed Summary
The purpose of this study is to estimate the relative bioavailability of nirmatrelvir/ritonavir of 4 different FDC tablet formulations relative to the commercial tablet formulation under fasted conditions in healthy adult participants.
Study Details
Timeline
Interventions
Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition