At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Prospective Single-blind Placebo-controlled Trial to Establish the Efficacy and Tolerability of 10% Povidone-Iodine for Nasal S. Aureus and Methicillin Resistant S. Aureus (MRSA) Decolonization Among Patients Undergoing Same-day Surgery
In Brief
A Phase 4 clinical trial evaluating Povidone-Iodine 10% and 0.9% NaCl Solution for Surgical Wound Infection and 2 related conditions. Completed, enrolled 192 participants across 1 site.
Detailed Summary
To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA. To determine whether a more convenient, single-dose, pre-operative 10% povidone-iodine (PI) application is effective in reducing nasal carriage of S. aureus and MRSA. We expect a statistically significant decrease in S. aureus/MRSA colonization in nasal cultures taken perioperatively after intervention in patients who received pretreatment with PI as compared to patients who received normal saline (NS).
Study Details
Timeline
Interventions
Nasal swab stick application of Povidone-Iodine 10% prior to surgery
Nasal swab stick application of 0.9% NaCl Solution prior to surgery