CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 160 enrolled
Drug / intervention
Fentanyl +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05533229
NCT05533229N/ACompleted

Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Perioperative Analgesia, Side Effects and Patient 's Satisfaction

Dr. Mihai Octavian Botea·observational·Posted Sep 8, 2022·Updated Aug 30, 2023

In Brief

An observational study evaluating Fentanyl and Morphine for Anesthesia. Completed, enrolled 160 participants across 1 site.

Detailed Summary

Intrathecal morphine and fentanyl are used for anesthesia and perioperative pain management in caesarian section. Despite the fact that spinal Fentanyl is better tolerated, might not be enough for postoperative pain control. Morphine offers an improved analgesia but might be not tolerated due to a higher incidence of side effects, especially nausea and vomiting. This is a prospective, randomized, double-blind, parallel study including 80 parturients scheduled for elective CS. Spinal anesthesia is consisting in bupivacaine (7.5 - 10 mg in relation to height) and either fentanyl 25 mcg (F group) either morphine 100 mcg (m group). It will be assessed intraoperative and postoperative pain scores, the incidence of sides effects, patient's satisfaction and systemic opioids consumption.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsAnesthesia
CountriesRomania

Timeline

N/ACompletedFinished
2023202420252026
First PostedSep 8, 2022
Enrollment StartApr 1, 2022
Primary CompletionAug 1, 2023
Study CompletionAug 10, 2023
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.8 years ago

Interventions

Fentanyldrug

The trial aims to study the quality of anesthesia and perioperative analgesia and patient's satisfaction provided by fentanyl and bupivacaine versus morphine and bupivacaine.

Morphinedrug

The trial aims to study the quality of anesthesia, perioperative analgesia and patient's satisfaction provided by fentanyl and bupivacaine versus morphine and bupivacaine.