CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 104 enrolled
Drug / intervention
Semaglutidedrug
Likely dose
Semaglutide 0.5 mg or 1.0 mg subcutaneous injection once weekly (dose escalation over 24 weeks)AI-extracted
Key inclusion· 5
  • Type 2 diabetes diagnosed ≥90 days before screening
  • Stable daily dose of oral antidiabetic drug (OAD) and/or insulin ≥60 days before screening
  • HbA1c 7.5–10% (59–86 mmol/mol)
  • Semaglutide indicated per approved local label
Key exclusion· 10
  • Prior glucagon-like peptide-1 receptor agonist (GLP-1 RA) medication
  • eGFR <30 mL/min/1.73 m²
  • Myocardial infarction, stroke, unstable angina, or transient ischemic attack within 180 days
  • NYHA Class IV heart failure

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05533632
NCT05533632Phase 4Completed

Safety and Tolerability of Weekly Semaglutide 0.5 mg or 1.0 mg in Chilean Subjects With Type 2 Diabetes

Novo Nordisk A/S·interventional·Posted Sep 9, 2022·Updated Sep 24, 2025

In Brief

A Phase 4 clinical trial evaluating Semaglutide for Diabetes Mellitus, Type 2. Completed, enrolled 104 participants across 3 sites.

Detailed Summary

This study is testing the safety and tolerability of subcutaneous semaglutide in participants with type 2 diabetes (T2D) in Chile. Participants will get a once-weekly subcutaneous injection of semaglutide in doses decided by the study doctor's criteria, according to participant's personal needs. The study will last for about 24 weeks. Participants will have 4 clinic visits and 2 phone calls. Participants will have 3 laboratory tests during the study (blood and urine samples).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChile
Collaborators--

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedSep 9, 2022
Enrollment StartApr 25, 2022
Primary CompletionJan 18, 2024
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 3.8 years ago

Interventions

Semaglutidedrug

Participants will receive semaglutide s.c. injection once weekly in a dose escalation manner for 24 weeks.