CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 21 enrolled
Drug / intervention
SGLT2 inhibitor +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05541484
NCT05541484Phase 4Completed

Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency

Washington University School of Medicine·interventional·Posted Sep 15, 2022·Updated Feb 21, 2025

In Brief

A Phase 4 clinical trial evaluating SGLT2 inhibitor and Biosense Breath Ketone Analyzer for Diabetes Mellitus, Type 1. Completed, enrolled 21 participants across 1 site.

Detailed Summary

This proposed study will test whether measurement of breath acetone (BrAce) can be used for the purpose of identifying ketosis (elevated ketones) in persons with type 1 diabetes (T1D). This is important for the potential use of sodium glucose co-transport inhibitors (SGLT2i) in persons with T1D.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedSep 15, 2022
Enrollment StartOct 14, 2022
Primary CompletionDec 23, 2023
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.8 years ago

Interventions

SGLT2 inhibitordrug

See above.

Biosense Breath Ketone Analyzerdevice

The hand-held device tests ketones in exhaled breath