CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,118 enrolled
Drug / intervention
Suzetrigine (SUZ) +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05558410
NCT05558410Phase 3Completed

A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Suzetrigine for Acute Pain After an Abdominoplasty

Vertex Pharmaceuticals Incorporated·interventional·Posted Sep 28, 2022·Updated Jul 1, 2025

In Brief

A Phase 3 clinical trial evaluating Suzetrigine (SUZ), HB/APAP, and 2 other interventions for Acute Pain. Completed, enrolled 1,118 participants across 12 sites.

Detailed Summary

The purpose of this study was to evaluate the efficacy and safety of Suzetrigine (SUZ) in treating acute pain after an abdominoplasty.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Pain
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedSep 28, 2022
Enrollment StartOct 10, 2022
Primary CompletionAug 25, 2023
Study CompletionSep 11, 2023
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 3.8 years ago

Interventions

Suzetrigine (SUZ)drug

Tablets for oral administration.

HB/APAPdrug

Capsules for oral administration.

Placebo (matched to SUZ)drug

Placebo matched to SUZ for oral administration.

Placebo (matched to HB/APAP)drug

Placebo matched to HB/APAP for oral administration.