CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 508 enrolled
Drug / intervention
Elranatamab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05565391
NCT05565391N/ACompleted

Comparative Effectiveness of Elranatamab (PF 06863135) in Clinical Study C1071003 Versus Standard of Care (SOC) in Real-World (RW) External Control Arms in Patients With Triple-Class Refractory (TCR) Multiple Myeloma (MM)

Pfizer·observational·Posted Oct 4, 2022·Updated May 21, 2024

In Brief

An observational study evaluating Elranatamab and Standard of care for Multiple Myeloma. Completed, enrolled 508 participants across 1 site.

Detailed Summary

This study is to understand how well elranatamab (PF-06863135) may be used for relapsed refractory multiple myeloma (RRMM). Sometimes MM might improve at first, but then gets resistant to the treatment and starts growing again (known as relapsed refractory). This study medicine will be compared with standard-of-care (SOC) therapies used in real-world clinical practice. For people receiving elranatamab, we will use data from the phase 2 clinical trial (MagnetisMM-3). We will also use data from two real-world databases, representing the SOC in clinical practice. This study does not seek any participants for enrollment. We will compare the experiences of people receiving elranatamab to people receiving SOC therapies. This way, it will help us to know how well elranatamab can be used for RRMM treatment.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedOct 4, 2022
Enrollment StartOct 3, 2022
Primary CompletionNov 4, 2022
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 3.7 years ago

Interventions

Elranatamabdrug

BCMA-CD3 bispecific antibody

Standard of caredrug

Standard of care