CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Brushingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05569850
NCT05569850N/ACompleted

In Vivo Evaluation of Antibacterial Toothpaste Efficiency and Patients' Satisfaction: a Double-blind Randomised Controlled Trial

University of Bologna·interventional·Posted Oct 6, 2022·Updated Apr 29, 2025

In Brief

A clinical study evaluating Brushing for Caries and Gingivitis. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The primary objective of this randomized controlled clinical trial (RCCT) will be to compare the efficacy in reducing the quantity of Streptococcus mutans (S. Mutans) in saliva of a recently introduced toothpaste compared to a commercially available toothpaste. The secondary outcomes will be to assess patients' impression of the toothpastes (in terms of taste, satisfaction etc.), and to investigate potential changes in dentin hypersensitivity, plaque formation and gingival inflammation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCaries, Gingivitis
CountriesItaly
CollaboratorsUnilever R&D

Timeline

N/ACompletedFinished
2023202420252026
First PostedOct 6, 2022
Enrollment StartDec 1, 2022
Primary CompletionJul 15, 2023
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 3.7 years ago

Interventions

Brushingother

Brushing the teeth 2x a day for 4 weeks.