CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 9,159 enrolled
Drug / intervention
patterns of use of combination therapy and monotherapyother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05576051
NCT05576051N/ACompleted
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Epidemiology and Efficacy of TNFi Combination Therapy (MTX+TNFi), TNFi Monotherapy, Tofacitinib Combination Therapy and Tofacitinib Monotherapy

Pfizer·observational·Posted Oct 12, 2022·Updated Dec 23, 2025

In Brief

An observational study evaluating patterns of use of combination therapy and monotherapy for Rheumatoid Arthritis. Completed, enrolled 9,159 participants across 1 site.

Detailed Summary

To estimate the efficacy of treatment with TNFi as monotherapy or combination therapy with MTX and compare and contrast efficacy with Tofacitinib as monotherapy and combination therapy in a real world setting.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsRheumatoid Arthritis
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedOct 12, 2022
Enrollment StartJun 4, 2015
Primary CompletionOct 7, 2015
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 3.7 years ago

Interventions

patterns of use of combination therapy and monotherapyother