CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 45 enrolled
Drug / intervention
Platelet-rich Plasma +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05579665
NCT05579665Phase 2Completed
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Comparative Effectiveness of Platelet Rich Plasma (PRP), Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome and Hyaluronic Acid (HA) for the Treatment of Knee Osteoarthritis

Universitas Sriwijaya·interventional·Posted Oct 14, 2022·Updated May 22, 2026

In Brief

A Phase 2 clinical trial evaluating Platelet-rich Plasma, Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome, and 1 other intervention for Knee Osteoarthritis. Completed, enrolled 45 participants across 1 site.

Detailed Summary

The clinical trial will be carried out at the Dr. Moh. Hoesin Central Hospital, Palembang and planned from October 2022 to March 2023. This study aims to compare the efficacy of Platelet Rich Plasma, Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell (MSC) Culture Secretome and hyaluronic acid for the Treatment of Knee Osteoarthritis

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis
CountriesIndonesia
CollaboratorsDr. Mohammad Hoesin Central General Hospital

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedOct 14, 2022
Enrollment StartOct 2, 2022
Primary CompletionMar 31, 2023
Study CompletionMay 31, 2023
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 3.7 years ago

Interventions

Platelet-rich Plasmabiological

Research participants own blood will be used to prepare the platelet rich plasma injectate.

Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretomebiological

Conditioned Medium UC-MSCs Secretome which will be injected into the affected knee using ultrasound guidance.

Low Molecular Weight Hyaluronic Aciddrug

low molecular weight hyaluronic acid which will be injected into the affected knee using ultrasound guidance.