CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 28 enrolled
Drug / intervention
CTI-1601 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05579691
NCT05579691Phase 2Completed

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Exploration Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous CTI-1601 in Adult Subjects With Friedreich's Ataxia

Larimar Therapeutics, Inc.·interventional·Posted Oct 14, 2022·Updated Nov 29, 2024

In Brief

A Phase 2 clinical trial evaluating CTI-1601 and Placebo for Friedreich Ataxia. Completed, enrolled 28 participants across 1 site.

Detailed Summary

To evaluate the safety and tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of subcutaneous (SC) administration of CTI-1601 over 28 days in subjects with Friedreich's ataxia (FRDA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedOct 14, 2022
Enrollment StartSep 21, 2022
Primary CompletionDec 4, 2023
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.7 years ago

Interventions

CTI-1601biological

CTI-1601 is a recombinant fusion protein and is intended to deliver human frataxin, the protein deficient in Friedreich's ataxia

Placeboother

Placebo Comparator