CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 18 enrolled
Drug / intervention
Inspiratory Muscle Training (IMT)device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05582642
NCT05582642N/ACompleted

Respiratory Muscles After Inspiratory Muscle Training in Patients After COVID-19 With Persistent Dyspnea and Respiratory Muscle Dysfunction

RWTH Aachen University·interventional·Posted Oct 17, 2022·Updated Jan 28, 2026

In Brief

A clinical study evaluating Inspiratory Muscle Training (IMT) for COVID-19 and Diaphragm Injury. Completed, enrolled 18 participants across 1 site.

Detailed Summary

It is the aim of the current (follow-up) project for the first time in post-COVID-19 patients who continue to complain of shortness of breath and for whom there is no other explanation than possibly proven diaphragmatic weakness, to determine the effects of 6 weeks of IMT/diaphragm training on diaphragm strength and shortness of breath.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany

Timeline

N/ACompletedFinished
2023202420252026
First PostedOct 17, 2022
Enrollment StartOct 17, 2022
Primary CompletionJun 1, 2024
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 3.7 years ago

Interventions

Inspiratory Muscle Training (IMT)device

The training itself includes 2 x 30 breathing cycles per day. The whole training should take place daily, 7 days a week. The initial training intensity in the treatment arm (resistance of the respiratory muscle training) is set to 50% of the maximum respiratory muscle strength (measured using PImax). Once a week the present investigators get a picture of patient's training, pay attention to shortness of breath, potential for adaptation. In the "control" arm of the study, this force adjustment would not take place, i.e. it is an endurance training of the diaphragm (10% of PI Max over the whole 6 weeks) with, however, also the control dates of the training twice a week. At least in the 6 weeks of the study (see above).