CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 500 enrolled
Drug / intervention
MLHFQ (Minnesota Living with Heart Failure Questionnaire) +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05583513
NCT05583513N/ACompleted

Evaluation of the Progression of Disease and Health-related Quality of Life in Ambulatory Heart Failure Patients: A Local Clinic-based Registry

Chinese University of Hong Kong·observational·Posted Oct 17, 2022·Updated May 30, 2025

In Brief

An observational study evaluating MLHFQ (Minnesota Living with Heart Failure Questionnaire) and KCCQ (the Kansas City Cardiomyopathy Questionnaire) for Heart Failure. Completed, enrolled 500 participants across 1 site.

Detailed Summary

Heart failure (HF) is a highly prevalent conditions that impose a significant burden to the patients, the hospital and the healthcare system. In Hong Kong, HF was one of the commonest causes of hospitalization and death. While HF with reduced ejection fraction (HFrEF) infer high mortality, HF with preserved ejection fraction (HFpEF) can be equally debilitating with similar hospital readmission rate and decline in functional status. Despite recent advancement and approval of novel pharmacologic agents and device therapies to treat HF, HF remains difficult to manage, with increased mortality and frequent hospitalization. HF is characterized by a gradual progression with intervals of exacerbation that often necessitating frequent re-admission. These readmissions are common with up to 1 quarter of patients readmitting within 30 days and half within 6 months8. An ambulatory HF centre can serve both as a transition of care from inpatients to community setting and as a point-of-care for early HF exacerbation (HFE) to prevent recurrent HF hospitalization. This is a registry study aims to investigate the progression disease and its impact on the quality of life (QoL) of the patients who are managed at the ambulatory HF clinic.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure
CountriesHong Kong
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedOct 17, 2022
Enrollment StartOct 1, 2022
Primary CompletionOct 1, 2023
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 3.7 years ago

Interventions

MLHFQ (Minnesota Living with Heart Failure Questionnaire)other

The MLHFQ, a 21-item HF-specific questionnaire, was adopted to evaluate the quality of life of the study subjects with score ranging 0-105 and lower the scores the better QoL

KCCQ (the Kansas City Cardiomyopathy Questionnaire)other

The KCCQ, is a 23-item self-administered questionnaire developed to independently measure the patient's perception of their health status, with score ranging 1-100 and higher scores the better QoL