CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 607 enrolled
Drug / intervention
Ritlecitinib +1 moredrug
Likely dose
Ritlecitinib 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05583526
NCT05583526Phase 3Completed

A PHASE 3 RANDOMIZED, DOUBLE-BLIND, 52-WEEK PLACEBO-CONTROLLED, MULTI-CENTER STUDY INVESTIGATING THE EFFICACY, SAFETY, AND TOLERABILITY OF RITLECITINIB IN ADULT AND ADOLESCENT PARTICIPANTS WITH NON SEGMENTAL VITILIGO

Pfizer·interventional·Posted Oct 17, 2022·Updated Feb 27, 2026

In Brief

A Phase 3 clinical trial evaluating Ritlecitinib and Placebo for Stable Nonsegmental Vitiligo and Active Nonsegmental Vitiligo. Completed, enrolled 607 participants across 115 sites in 15 countries.

Detailed Summary

A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents with Nonsegmental Vitiligo (Active and Stable) Tranquillo

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Bulgaria, Canada, China, Germany, Italy, Japan, Mexico, Poland, South Africa, South Korea, Spain, Turkey (Türkiye), United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedOct 17, 2022
Enrollment StartDec 1, 2022
Primary CompletionFeb 5, 2026
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 3.7 years ago

Interventions

Ritlecitinibdrug

50 mg capsule

Placebodrug

Matching capsule