CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 124 enrolled
Drug / intervention
dupilumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05590585
NCT05590585Phase 4Completed

An Open-Label Single-Arm Study of Dupilumab in Adolescent and Adult Skin of Color Patients With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals·interventional·Posted Oct 21, 2022·Updated May 27, 2026

In Brief

A Phase 4 clinical trial evaluating dupilumab and Topical emollient (moisturizer) for Moderate-to-Severe Atopic Dermatitis and Atopic Eczema. Completed, enrolled 124 participants across 30 sites.

Detailed Summary

The study is focused on skin of color participants who have moderate-to-severe atopic dermatitis. Atopic dermatitis, also referred to as eczema, is a condition that causes the skin to become itchy, dry, and cracked. From the previous studies on the study drug, it is seen that the study drug has an acceptable safety and effectiveness in participants with atopic dermatitis. The aim of this study is to get additional information on the safety and effectiveness of the study drug, particularly the information on aspects of atopic dermatitis in skin of color participants. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in your blood at different times * How much the study drug improves quality of life and mental health

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsSanofi

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedOct 21, 2022
Enrollment StartJan 11, 2023
Primary CompletionNov 14, 2024
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 3.7 years ago

Interventions

dupilumabdrug

Administered by subcutaneous (SC) injection once every 2 weeks (Q2W) following a loading dose

Topical emollient (moisturizer)other

Moisturizer should be applied twice daily, as per physician's recommendation, as defined in protocol.