CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 27 enrolled
Drug / intervention
Active cooling device with cooling plate +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05595213
NCT05595213N/ACompleted

Pilot Evaluation of Wrist Cooling Devices on the Severity of Hot Flashes for Women and Men Who Suffer From Moderate and or Severe Hot Flashes

Boston University·interventional·Posted Oct 26, 2022·Updated Dec 1, 2025

In Brief

A clinical study evaluating Active cooling device with cooling plate, Placebo device without cooling plate, and 1 other intervention for Hot Flashes. Completed, enrolled 27 participants across 1 site.

Detailed Summary

This pilot study aims to determine the impact of an experimental active cooling wrist device compared to a placebo device \[the devices look identical\] on symptom control of hot flashes in adult men and adult women experiencing hot flashes. The participants will record during the first two weeks of the study all of their hot flashes and severity of their hot flashes in a study diary. Each participant will wear each of the two devices \[active cooling and placebo\] during the trial but the order of which device they wear first will be determined by their random assignment into a group. The devices are identical in appearance and neither the participant nor the investigators w ill know which device the participants are wearing. Participants will wear the first assigned device for weeks 3 and 4. They will record in their diary the severity of their hot flashes while using the device. For weeks 5 and 6 they will use a second device and record in their diary the severity of their hot flashes with the use of the device. The devices will be attached to the wrist like a watch. When activated, the experimental active cooling device will turn on a cooling fan with the cooling plate being active for up to 5 minutes. In contrast, the placebo device will only turn on a cooling fan for up to 5 minutes without the cooling plate being active.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHot Flashes
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedOct 26, 2022
Enrollment StartMar 5, 2023
Primary CompletionJan 2, 2025
Study CompletionJan 13, 2025
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 3.7 years ago

Interventions

Active cooling device with cooling platedevice

This device is worn like a watch and pressing the button activates the cooling function to begin to cool the wrist skin temperature to 47 degrees. Pushing the device button again cools the skin to 60 degrees and a third time to 77degrees.

Placebo device without cooling platedevice

This device is worn like a watch and pressing the button activates the cooling fan for 5 minutes.

Hot Flash Diaryother

Participants will be instructed to document each hot flash experience daily and indicate if it was mild, moderate, or severe and whether they activated the wrist cooling device.