CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled / 20 target
Drug / intervention
Drug: Growth Factors (CGF) +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05595772
NCT05595772N/ACompletedUpdate Overdue (0.4/mo)Completion was 35mo ago

PRGF VS CGF in Management of Labial Dehiscence Around Immediate Implants (Comparative Study) {PRGF= Plasma Rich in Growth Factors } {CGF=Concentrated Growth Factor}

Minia University·interventional·Posted Oct 27, 2022·Updated Jun 9, 2026

In Brief

A clinical study evaluating Drug: Growth Factors (CGF), Drug: Growth Factors (PRGF), and 3 other interventions for Dental Implant Failure Nos. Completed, enrolled 20 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

The goal of this clinial trial is to detect Which one of two different platelet concentrate bio-membrane (first or third generation) is better in terms of marginal bone level and bone density around immediate implants in esthetic zone using Cone beam computerized tomography The plasma rich in growth factor or concentrated growth factor? 20 patients with nonrestorable maxillary tooth in the esthetic zone, Subjects will be enrolled The study will use simple randomization to allocate patients into 2 groups, each group will be included 10 patients: Group A: (concentrated growth factor group) ten patients indicated for immediate implant in the maxillary anterior region (class II socket), will be a candidate for immediate implant placement with CGF combined with xenogeneic bone graft Group B: (platelet-rich in growth factor group) Ten patients who indicated immediate implant in the maxillary anterior region (class I or class II socket), will be a candidate for immediate implant placement with PRGF combined with xenogeneic bone graft.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedOct 27, 2022
Enrollment StartFeb 1, 2022
Primary CompletionJul 30, 2023
Study CompletionAug 30, 2023
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 3.7 years ago

Arms & Interventions

group A (Concentrated Growth Factor) CGFactive_comparator

ten patients indicated for immediate implant in the maxillary anterior region (class II socket)

Drug: Drug: Growth Factors (CGF)Procedure: Surgery: Dental Implant surgeryProcedure: Tooth extractionProcedure: Xenogenic bone grafting
group B (Plasma Rich in Growth Factor) PRGFactive_comparator

Ten patients who indicated immediate implant in the maxillary anterior region (class I or class II socket),

Drug: Drug: Growth Factors (PRGF)Procedure: Surgery: Dental Implant surgeryProcedure: Tooth extraction

Interventions

Drug: Growth Factors (CGF)drug

Application of biological membrane of Concentrated growth factor (CGF) over bone grafting and implant

Drug: Growth Factors (PRGF)drug

Application of biological membrane of Plasma rich in growth factors combined with Xenogeneic bone grafting material around immediate implant

Surgery: Dental Implant surgeryprocedure

Immediate implant following extraction

Tooth extractionprocedure

A Traumatic tooth extraction

Xenogenic bone graftingprocedure

Application of bovine bone grafting over area of dehiscence around immediate implant