CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 158 enrolled
Drug / intervention
Hexaminolevulinate Hydrochloride +1 moredrug
Likely dose
Hexaminolevulinate hydrochloride 50 mL intravesical solution instilled for one hourAI-extracted
Key inclusion· 2
  • Suspicious or confirmed bladder cancer diagnosis
  • Age 18 years or older
Key exclusion· 7
  • Gross hematuria that may impair visualization (light hematuria allowed if manageable)
  • BCG immunotherapy or intravesical chemotherapy within past 6 weeks
  • History of porphyria
  • Known allergy to hexaminolevulinate hydrochloride or similar compounds

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05600322
NCT05600322Phase 3Completed

A Prospective, Comparative Within Patient Controlled, Multi-center Study of Hexvix Blue Light Cystoscopy and White Light Cystoscopy in the Detection of Bladder Cancer

Photocure·interventional·Posted Oct 31, 2022·Updated Oct 3, 2024

In Brief

A Phase 3 clinical trial evaluating Hexaminolevulinate Hydrochloride and Richard Wolf Photodynamic Diagnostic Equipment (PDD) system for Bladder Cancer. Completed, enrolled 158 participants across 7 sites.

Detailed Summary

A study to compare Hexvix Blue light cstoscopy with standard White light cystoscopy in the detection of bladder cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBladder Cancer
CountriesChina

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedOct 31, 2022
Enrollment StartNov 3, 2022
Primary CompletionJul 12, 2023
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 3.7 years ago

Interventions

Hexaminolevulinate Hydrochloridedrug

Enrolled patients will be instilled with 50 mL hexaminolevulinate hydrochloride as intravesical solution (Hexvix) in the bladder for one hour at Visit 2. After bladder evacuation, the cystoscopic examinations will be performed in both white and blue light.

Richard Wolf Photodynamic Diagnostic Equipment (PDD) systemdevice

Cystoscopy in White and Blue light will be done using the Richard Wolf PDD system.