CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 17 enrolled
Drug / intervention
Transcutaneous Non-Invasive Vagus Nerve Stimulationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05608629
NCT05608629N/ACompleted

Vagus Nerve Stimulation as Treatment for Long Covid

Icahn School of Medicine at Mount Sinai·interventional·Posted Nov 8, 2022·Updated Jan 8, 2024

In Brief

A clinical study evaluating Transcutaneous Non-Invasive Vagus Nerve Stimulation for Long COVID and Chronic Fatigue Syndrome. Completed, enrolled 17 participants across 1 site.

Detailed Summary

Many patients do not recover following Covid infection. The resulting illness is called Long Covid. Because there is no agreed upon treatment for this ailment, the research team has decided to do an open label pilot study using non-invasive, transcutaneous stimulation of the auricular branch of the vagus nerve. Inclusion criteria required the patient to fulfill criteria for having chronic fatigue syndrome. To date, fourteen patients provided evaluable data. Eight of these fulfilled the study's requirements for treatment success.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedNov 8, 2022
Enrollment StartJun 6, 2022
Primary CompletionDec 5, 2022
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 3.6 years ago

Interventions

Transcutaneous Non-Invasive Vagus Nerve Stimulationdevice

The parasym is a system for delivering a fixed signal to stimulate the auricular branch of the vagus nerve. The device used is available without prescription in UK and EU. Similar devices have been used to treat migraine and one is in testing to be used for atrial fibrillation.