At a glance
ClinicalIndex Comparison Record- ✓Age less than 12 months at hospital admission
- ✓First-time hospitalization for bronchiolitis
- ✓One primary residence occupied >5 days per week
- ✓Electricity available in the home to power study equipment
- ✕Chronic airway or respiratory conditions requiring home oxygen, mechanical ventilation, or tracheostomy dependence
- ✕Known immunodeficiency or hemodynamically significant cardiac conditions requiring medication or oxygen
- ✕Cystic fibrosis or neuromuscular disease
- ✕Eligible for palivizumab per AAP guidelines
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Bronchiolitis Recovery and the Use of High Efficiency Particulate Air (HEPA) Filters
In Brief
A clinical study evaluating Winix 5500-2 HEPA filtration units for Bronchiolitis. Completed, enrolled 230 participants across 17 sites.
Detailed Summary
This is a multi-center, parallel, double-blind, randomized controlled clinical trial. Children \<12 months of age hospitalized with bronchiolitis are randomized 1:1 to receive a 24-week home intervention with filtration units containing HEPA and carbon filters (in the child's sleep space and a common room) to improve indoor air quality (IAQ) or to a control group with filtration units without HEPA and carbon filters. The HEPA intervention units and control units will be used for 24 weeks after pre-intervention IAQ measurements. Children are followed for respiratory outcomes over the pre-intervention and intervention periods.
Study Details
Timeline
Interventions
To determine if use of a HEPA filtration unit home intervention reduces the respiratory symptom burden (symptom-free days; SFD) for 24 weeks compared to a use of a control unit.