CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 21 enrolled
Drug / intervention
Sculptra +1 moredevice
Likely dose
Not stated in record
Key inclusion· 4
  • Minimum shallow nasolabial fold contour deficiencies as assessed by wrinkle assessment scale (WAS)
  • Identical WAS scores on both nasolabial folds (symmetric baseline)
  • Able to provide informed consent
  • Agreement to undergo skin biopsies on nasolabial folds
Key exclusion· 4
  • Significant nasolabial fold asymmetry or different WAS scores between sides
  • Pregnant, planning pregnancy, or breastfeeding
  • History of allergy or hypersensitivity to treatment product ingredients
  • History of allergy or hypersensitivity to anesthetics or lidocaine

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05620043
NCT05620043N/ACompleted

A Randomized, Single-center, Prospective Biopsy Study Comparing a Poly L-lactic Acid Biostimulator and a Calcium Hydroxylapatite Semi-permanent Filler

Galderma R&D·interventional·Posted Nov 17, 2022·Updated Apr 15, 2026

In Brief

A clinical study evaluating Sculptra and Radiesse Plus for Gene Expression. Completed, enrolled 21 participants across 1 site.

Detailed Summary

To compare gene expression stimulated by a semi-permanent filler and a biostimulator via punch biopsy

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGene Expression
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedNov 17, 2022
Enrollment StartSep 28, 2022
Primary CompletionJul 25, 2023
Study CompletionNov 6, 2023
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 3.6 years ago

Interventions

Sculptradevice

Biostimulator

Radiesse Plusdevice

Semi-permanent filler