At a glance
ClinicalIndex Comparison Record- ✓Chronic rhinitis symptoms (rhinorrhea, congestion, post-nasal drip) for at least 6 months
- ✓Poor response to medical management attempted for at least 4 weeks
- ✓rTNSS score ≥6 with rhinorrhea ≥2 and congestion ≥1
- ✕Active sinusitis
- ✕Rhinitis medicamentosa (medication-induced rhinitis)
- ✕Recurrent and ongoing epistaxis (nosebleeds)
- ✕Immunodeficiency or history of sinus surgery
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
In Brief
A clinical study evaluating Radiofrequency ablation (RFA) for Chronic Rhinitis. Completed, enrolled 17 participants across 1 site.
Detailed Summary
The purpose of this study is to assess the effectiveness of radiofrequency ablation (RFA) of the posterior nasal nerve (PNN) in chronic rhinitis (CR) patients by comparing patient reflective total nasal symptom score (rTNSS) and nasal obstruction symptom evaluation (NOSE) , peak nasal inspiratory flow (PNIF) , and levels of Type 2 cytokines pre- and post-procedure.
Study Details
Timeline
Interventions
The NEUROMARK device is an in-office, disposable bipolar RFA device with a treatment tip consisting of micro electrodes which delivers RF energy while monitoring appropriate tissue contact to maximize delivery to posterior nasal nerve and its variable branching. After topical anesthesia consisting of oxymetazoline and 1% lido followed by 4% lidocaine, the device will be placed in the posterior inferior turbinate under endoscopic visualization. The device will be activated per manufacturer's instructions