CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
Metformin +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05653895
NCT05653895N/ACompleted

Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS:A Double Blind Randomized Placebo Controlled Trial

Khyber Medical University Peshawar·interventional·Posted Dec 16, 2022·Updated Feb 23, 2024

In Brief

A clinical study evaluating Resveratrol, Metformin, and 1 other intervention for PCOS. Completed, enrolled 120 participants across 1 site.

Detailed Summary

The investigators aim to conduct a double blind randomized clinical trial to study the independent and additive effects of micronutrients (Resveratrol, Acetyl-L Carnitine, L Arginine and COQ10 ) with Metformin in patients with PCOS .Women diagnosed with PCOS according to National Institute of Health( NIH) 2012 extension of European Society of Human Reproduction and Embryology /American Society of Reproductive Medicine ESHRE /ASRM 2003 criteria will be included according to a specific phenotype including Hyperandrogenism, Ovulatory dysfunction and Polycystic Ovarian Morphology. The investigators propose that by using combination therapy with micro supplements like Resveratrol, Acetyl-L Carnitine, L Arginine and COQ10 will produce greater improvement better than or at least comparable to Metformin in metabolic and endocrine profile of patients with PCOS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPCOS
CountriesPakistan
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedDec 16, 2022
Enrollment StartDec 7, 2022
Primary CompletionDec 30, 2023
Study CompletionFeb 7, 2024
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 3.5 years ago

Interventions

Resveratroldietary

Resveratrol

Metformindrug

Metformin

Acetyl-L-Carnitin, L Arginine, Co-Q10combination

Treatment of PCOS with combination of Acetyl-L-Carnitin, L Arginine, Co-Q10