CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 197 enrolled
Drug / intervention
Corsodyl Original Dentifrice +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05654662
NCT05654662N/ACompleted

A Randomized, Controlled, Examiner-Blind Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal

HALEON·interventional·Posted Dec 16, 2022·Updated Jan 13, 2025

In Brief

A clinical study evaluating Corsodyl Original Dentifrice and Colgate Cavity Protection Dentifrice for Gingivitis and Dental Plaque. Completed, enrolled 197 participants across 1 site.

Detailed Summary

The main goal of this study is to evaluate and compare the efficacy of an on-market dentifrice containing 67 percent (%) sodium bicarbonate and 0.31% sodium fluoride to a reference regular fluoride dentifrice on treating gingival bleeding and gingival inflammation as well as reducing plaque accumulation in population with gingivitis after 12 weeks use.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedDec 16, 2022
Enrollment StartFeb 20, 2023
Primary CompletionNov 30, 2023
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 3.5 years ago

Interventions

Corsodyl Original Dentifricedrug

It contains 67% weight/weight (w/w) Sodium Bicarbonate and 0.310% w/w Sodium Fluoride (1400 parts per million \[ppm\] Fluoride ion \[F\])

Colgate Cavity Protection Dentifricedrug

It contains 0.76% w/w Sodium Monofluorophosphate (1000 ppm F) and 0.1% w/w Sodium Fluoride (450 ppm F)