CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 62 enrolled
Drug / intervention
Combination mindfulness spiritual-based cognitive therapy plus hypnosis +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05659472
NCT05659472N/ACompleted

The Effect of Combination Mindfulness Spiritual-Based Cognitive Therapy Plus Hypnosis on Levels of Cortisol, Serotonin, and Depression Degree in HIV Patients With Depression

Health Technology Institute of Cendekia Utama Kudus·interventional·Posted Dec 21, 2022·Updated Dec 21, 2022

In Brief

A clinical study evaluating Combination mindfulness spiritual-based cognitive therapy plus hypnosis and Mindfulness-based cognitive therapy for Depression. Completed, enrolled 62 participants across 1 site.

Detailed Summary

HIV/AIDS patients are at risk for depression, a multifactorial disorder with signs and symptoms that affect the cognitive, affective, behavioral, and somatic areas. This study used Randomized Controlled Clinical Trials (RCT). Main hypothesis: A combination of spiritual awareness-based cognitive therapy (MSBCT) plus hypnotic interventions can reduce depression degree scores by reducing cortisol levels and increasing serotonin levels in HIV patients with depression. Small hypothesis 1. There was a decrease in cortisol levels after being given the MSBCT plus hypnosis combination intervention in HIV patients with depression; 2. There was an increase in serotonin levels after being given the MSBCT plus hypnosis combination intervention in HIV patients with depression; 3. There was a decrease in depression degree scores after being given the MSBCT plus hypnosis combination intervention in HIV patients with depression; 4. There was a higher reduction in cortisol levels in the intervention group compared to the control group in HIV patients with depression; 5. There was a higher increase in serotonin levels in the intervention group compared to the control group in HIV patients with depression; 6. There was a higher reduction in scores degree of depression in the intervention group compared to the control group in HIV patients with depression; 7. Decreased cortisol levels and increased serotonin levels affect depression degree scores in HIV patients with depression; 8. MSBCT plus hypnosis combination intervention is a factor that can affect depression degree scores reduction in HIV patients with depression;

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression
CountriesIndonesia
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 21, 2022
Enrollment StartDec 12, 2020
Primary CompletionApr 10, 2021
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 3.5 years ago

Interventions

Combination mindfulness spiritual-based cognitive therapy plus hypnosisbehavioral

The intervention was divided into eight components in eight sessions, namely (1) psychoeducation and intention, (2) awareness of breathing mindfulness, (3) body scan, (4) comfort training through daily activity/comfort exercises, (5) self-compassion / having a great soul with acceptance, gratitude, and sincerity, (6) planning happiness through independent healthy behavior targets, (7) independent healthy behavior (8) independent healthy behavior evaluation. Each therapeutic component of each session is further divided into three sub-components, namely psychoeducation, training, and hypnosis.

Mindfulness-based cognitive therapybehavioral

The program curriculum consists of the automatic pilot; living in our heads; gathering the scattered mind; recognizing aversion; allowing and letting be; thoughts as thoughts; kindness in action; maintaining and extending new learning.