CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 795 enrolled
Drug / intervention
Insulin Efsitora Alfa +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05662332
NCT05662332Phase 3Completed

A Phase 3, Parallel-Design, Open-Label, Randomized Control Study to Evaluate the Efficacy and Safety of LY3209590 Administered Weekly Using a Fixed Dose Escalation Compared to Insulin Glargine in Insulin-Naïve Adults With Type 2 Diabetes

Eli Lilly and Company·interventional·Posted Dec 22, 2022·Updated Aug 6, 2025

In Brief

A Phase 3 clinical trial evaluating Insulin Efsitora Alfa and Insulin Glargine for Type 2 Diabetes and T2D. Completed, enrolled 795 participants across 71 sites in 4 countries.

Detailed Summary

The main purpose of this study is to determine the efficacy and safety of insulin efsitora alfa (LY3209590) administered weekly using a fixed dose escalation compared to insulin glargine in adults with type 2 diabetes (T2D) who are starting basal insulin therapy for the first time.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes, T2D
CountriesArgentina, Mexico, Puerto Rico, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedDec 22, 2022
Enrollment StartJan 14, 2023
Primary CompletionJul 19, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 3.5 years ago

Interventions

Insulin Efsitora Alfadrug

Administered SC

Insulin Glarginedrug

Administered SC