CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 55 enrolled
Drug / intervention
Lidocaine Hydrochloridedrug
Likely dose
Lidocaine Hydrochloride 10 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05670236
NCT05670236Phase 4Completed
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Effect of Knee Pain on Walking Biomechanics

The Cleveland Clinic·interventional·Posted Jan 4, 2023·Updated Oct 29, 2025

In Brief

A Phase 4 clinical trial evaluating Lidocaine Hydrochloride for Osteoarthritis, Knee. Completed, enrolled 55 participants across 1 site.

Detailed Summary

The goal of this study is to determine if pain in one knee influences loading of the other knee during different types of walking. The main questions it aims to answer are: * How does unilateral knee pain affect contralateral knee joint loading during different types of walking? * Does movement and loading change at the hips, knees, and ankles during prolonged walking in persons with painful knee osteoarthritis? Participants will: * Fill out questionnaires/surveys * Complete clinical examinations * Walking on a treadmill under different types of walking conditions * Receive two knee injections For comparison purposes, researchers will also enroll healthy participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis, Knee
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedJan 4, 2023
Enrollment StartJan 25, 2023
Primary CompletionJul 19, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 3.5 years ago

Interventions

Lidocaine Hydrochloridedrug

10 mL of 1% lidocaine hydrochloride for each intraarticular knee injection