CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Non-Interventionalother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05672030
NCT05672030N/ACompleted

Role of Interleukin 5 (IL-5) and IL-5R Signaling in Non-eosinophil Upper Airway Cells in Chronic Rhinosinusitis With Nasal Polyps

Brigham and Women's Hospital·observational·Posted Jan 5, 2023·Updated Nov 24, 2025

In Brief

An observational study evaluating Non-Interventional for Nasal Polyps and Aspirin-exacerbated Respiratory Disease. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The overarching hypothesis of this proposal is that IL-5 acts on multiple sinus tissue cell types, including plasma cells and epithelial cells, to promote immune dysregulation, and that inhibition of IL-5 affects several relevant effector pathways that lead to clinical benefit.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJan 5, 2023
Enrollment StartOct 1, 2022
Primary CompletionDec 1, 2023
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.5 years ago

Interventions

Non-Interventionalother

No intervention.