CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 100 enrolled
Drug / intervention
0.25% Bupivacaine +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05672680
NCT05672680Phase 3Completed
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Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs

Icahn School of Medicine at Mount Sinai·interventional·Posted Jan 5, 2023·Updated Mar 28, 2025

In Brief

A Phase 3 clinical trial evaluating 0.25% Bupivacaine, Placebo, and 1 other intervention for Inguinal Hernia. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The aim of this double-blind clinical trial is to examine outcomes and pain control after surgery in patients who underwent laparoscopic inguinal hernia repair (IHR) with the use of perioperative transabdominal plane (TAP) block. Research Question: Does transabdominal plane block improve pain when undergoing inguinal hernia repair? The endpoints include whether preoperative TAP blocks improve pain score (primary end point) and decrease opioid use (secondary endpoint) after an inguinal hernia repair. Other end points- complications after surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInguinal Hernia
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedJan 5, 2023
Enrollment StartDec 9, 2019
Primary CompletionAug 3, 2023
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 3.5 years ago

Interventions

0.25% Bupivacainedrug

received during TAP block

Placebodrug

placebo equivalent

TAP blockprocedure

The intervention is a transabdominal plane (TAP) block given in the abdomen to block pain receptors on nerves -during surgery can presumably decrease postoperative pain. Currently, TAP blocks are approved for use and performed based on surgeon preference (e.g. some surgeons perform them on every case, others variably, etc.).