CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
active tDCS paired with active MBM +1 moredevice
Likely dose
Active tDCS: 2 milliampere (mA) for 20 minutes per session, 5 sessions total, paired with active mindfulness-based meditationAI-extracted
Key inclusion· 4
  • ✓Undergoing elective unilateral knee total replacement
  • ✓Mentally capable of reading, giving consent, and following instructions
  • ✓Able to answer questions in English
  • ✓Not pregnant
Key exclusion· 6
  • ✕History of brain surgery, brain tumor, seizure, stroke, or intracranial metal implantation
  • ✕Systemic rheumatic disorders including rheumatoid arthritis, systemic lupus erythematosus, and fibromyalgia
  • ✕Alcohol or substance abuse
  • ✕Current use of sodium channel blockers, calcium channel blockers, or NMDA receptor antagonists

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05673720
NCT05673720N/ACompleted
CompareCT.gov

Feasibility, Acceptability, and Preliminary Efficacy of Combined Transcranial Direct Current Stimulation and Mindfulness for Pain After Total Knee Arthroplasty

Florida State University·interventional·Posted Jan 6, 2023·Updated Nov 24, 2025

In Brief

A clinical study evaluating active tDCS paired with active MBM and sham tDCS paired with sham MBM for Osteoarthritis, Knee. Completed, enrolled 24 participants across 1 site.

Detailed Summary

Feasibility, acceptability, and preliminary efficacy of combined transcranial direct current stimulation and mindfulness for pain after total knee arthroplasty

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis, Knee
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJan 6, 2023
Enrollment StartMay 15, 2023
Primary CompletionSep 25, 2024
Study CompletionOct 25, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 3.5 years ago

Interventions

active tDCS paired with active MBMdevice

Active tDCS with a constant current intensity of 2 milli ampere( mA)will be applied for 20 minutes per session for 5 times via the Soterix 1x1 tDCS mini-CT Stimulator device with headgear and saline-soaked surface sponge electrodes. The meditation intervention will be applied simultaneously with tDCS for 20 minutes per session for 5 times by a recorded meditation.

sham tDCS paired with sham MBMdevice

For sham stimulation, the electrodes will be placed in the same positions as for active stimulation, but the stimulator will only deliver 2 mA current for 30 seconds. The sham MBM intervention will be delivered via a CD player that will look identical in both active and sham MBM.