CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 77 enrolled
Drug / intervention
Advil PM Liqui-Gels Minis +1 moredrug
Likely dose
Advil PM Liqui-Gels Minis 200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05674721
NCT05674721Phase 1Completed

A Randomized, Open Label, Single Center, Single Dose, Two Treatment, Two Period, Two Sequence Crossover Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) To Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions

HALEON·interventional·Posted Jan 6, 2023·Updated Aug 23, 2024

In Brief

A Phase 1 clinical trial evaluating Advil PM Liqui-Gels Minis and Advil PM Liqui-Gels for Pain. Completed, enrolled 77 participants across 1 site.

Detailed Summary

The purpose of this study is to support the submission of Advil PM Liqui-Gels Minis (ibuprofen/diphenhydramine hydrochloride 200 milligrams \[mg\]/25 mg) which is a size reduction of the currently marketed Advil PM Liqui-Gels, by determining if this product is bioequivalent to the reference product Advil PM Liqui-Gels (ibuprofen/diphenhydramine hydrochloride 200 mg/25 mg) under fasting conditions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2023202420252026
First PostedJan 6, 2023
Enrollment StartJan 5, 2023
Primary CompletionMar 21, 2023
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 3.5 years ago

Interventions

Advil PM Liqui-Gels Minisdrug

Ibuprofen/diphenhydramine hydrochloride 200 mg/25 mg, Oral capsule which is a size reduction of the currently marketed reference product.

Advil PM Liqui-Gelsdrug

Ibuprofen/diphenhydramine hydrochloride 200 mg/25 mg, Oral capsule.