CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 105 enrolled
Drug / intervention
Behavioral Activation +2 morebehavioral
Likely dose
Not stated in record
Key inclusion· 3
  • Age ≥60 years
  • Scheduled major thoracic, breast, or abdominal surgery for suspected or confirmed malignancy
  • Clinically significant depression or anxiety symptoms (PHQ-ADS ≥10)
Key exclusion· 5
  • Unable to read, speak, and understand English
  • Severe cognitive impairment (Short Blessed Test >10)
  • Acutely suicidal
  • Ineligible per discretion of oncologic surgeon or study PI

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05685511
NCT05685511N/ACompleted

Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery

Washington University School of Medicine·interventional·Posted Jan 17, 2023·Updated Mar 31, 2026

In Brief

A clinical study evaluating Behavioral Activation, Medication Optimization, and 1 other intervention for Older Adults and 4 related conditions. Completed, enrolled 105 participants across 1 site.

Detailed Summary

Using a Hybrid Type 1 Effectiveness-Implementation randomized control trial (RCT) design, the investigators will test the effectiveness of a bundled behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing oncologic surgery (compared with usual care), while examining implementation outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedJan 17, 2023
Enrollment StartMar 10, 2023
Primary CompletionJul 12, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.5 years ago

Interventions

Behavioral Activationbehavioral

The behavioral intervention will consist of behavioral activation (BA), the basic premise of which is to help people with mental health problems to engage in activities that are reinforcing or meaningful and guided by their personal values

Medication Optimizationother

Medication optimization consists of a simple set of principles: reconcile patient's medications, identify the patient's likely need for, and interest in, a medication adjustment, make the adjustment, and assess the response to that adjustment.

Usual care resourcesother

List of resources that the patient can explore on their own